Losartan Potassium 50 mg + Hydrochlorthiazide -12.5 mg tabs.

• Essential hypertension
• Hypertension with concomitant diabetes
• Diabetic Nephropathy

2 tablets 3 times daily for 4-5 days of heavy menstrual blood loss with pain.

Losartan and its metabolite block the vasoconstrictor and aldosterone-secreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor. Hydrochlorothiazide, a thiazide diuretic affects the renal tabular mechanisms of electrolyte re-absorption, directly increasing excretion of sodium salt and chloride in approximately equivalent amounts.

COMMON

• Cardiovascular: Edema , Palpitations 
• Dermatologic: Rash
• Endocrine metabolic: Electrolyte imbalance
• Gastrointestinal: Abdominal pain, Diarrhea, Nausea
• Musculoskeletal: Backache 
• Neurologic: Asthenia, Dizziness, Headache
• Respiratory: Bronchitis, Cough, Pharyngitis, Sinusitis,     Upper respiratory infection
• Other: Fatigue      

• Hepatic: Hepatitis (rare)

• Angioedema (associated with aspirin and/or penicillin allergy)
• Avoid lithium
• Biliary cirrhosis or biliary obstruction
• Hyperuricemia or gout
• Hypotension, intravascular volume- and salt-depleted
• Liver disease
• May aggravate digitalis toxicity
• Renal artery stenosis; solitary kidney
• Hepatic or renal impairment
• Systemic lupus erythematosus

Tranexamic acid is contraindicated in patients with active intravascular clotting process, acquired defective color vision, subarachanoid hemorrhage, severe renal insufficiency and hypersensitivity to tranexamic acid.
Mefenamic acid is contraindicated: in patients with hypersensitivity to mefenamic acid, patients who have experienced asthma, urticaria, or allergic reaction after taking aspirin or other NSAID.

• Anuria
• Hypersensitivity to hydrochlorothiazide, losartan, or sulfonamides
  

Not safe to be used

Pack of 30 tabs / box (5x6).